Medical Researches
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Based on 27 Researches
Vitamin D3 reduces triglycerides and cholesterolEffect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
Highly relevant to cholesterol management
We evaluated how vitamin D3 supplementation influences cholesterol levels in overweight or obese women through a comprehensive meta-analysis of randomized controlled trials. Our focus was on understanding whether this vitamin could effectively improve lipid profiles, specifically high cholesterol levels.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
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We investigated how vitamin D3 supplements impact cholesterol levels in pediatric patients suffering from obesity. The study involved 723 children over two years, with 283 receiving vitamin D3 and 440 on a placebo.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
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We explored the impact of vitamin D3 on cholesterol levels, specifically in individuals taking olanzapine, an antipsychotic medication known to cause dyslipidemia, a condition characterized by abnormal lipid levels. By analyzing various sources including the FDA Adverse Event Reporting System and electronic medical records, we aimed to uncover whether vitamin D3 supplementation could alleviate the cholesterol imbalances caused by olanzapine.
Our findings revealed that vitamin D3 has a beneficial effect, helping to reduce the unfavorable changes in cholesterol levels typically induced by olanzapine. In particular, we noted that while olanzapine raised low-density lipoprotein (LDL) cholesterol and lowered high-density lipoprotein (HDL) cholesterol, vitamin D3 supplementation appeared to help restore balance in these lipid levels.
Further investigations into cellular mechanisms showed that vitamin D3 may work by inhibiting the cholesterol production process within certain cells. This aligns well with our overall goal of identifying effective treatment strategies that can positively affect cholesterol management in those affected by olanzapine treatment.
In summary, our comprehensive analysis suggests that vitamin D3 supplementation could serve as a promising adjunct therapy for managing cholesterol levels in patients prescribed olanzapine.
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We conducted an insightful study to examine the effects of cod liver oil on high cholesterol levels. The research was carried out in a well-structured manner, with 600 participants who had elevated cholesterol and low-density lipoprotein (LDL) levels. These individuals were divided into two groups. One group received daily doses of 415 mg of cod liver oil along with 10 mg of rosuvastatin, while the other group received just the rosuvastatin with placebo capsules.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
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Vitamin D3 improves cholesterol levelsThe Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial.
Directly investigates vitamin D and cholesterol
We conducted a double-blind, randomized clinical trial to investigate how vitamin D3 treatment influences cholesterol levels in patients with ischemic heart disease (IHD) who were also vitamin D deficient. In total, 44 patients participated, and we divided them into two groups: one received vitamin D3 supplements, while the other was given a placebo.
After a five-week treatment period, we observed some interesting results. In the group that received vitamin D3, levels of high-density lipoprotein (often referred to as “good cholesterol”) significantly increased, while triglycerides—a type of fat in the blood—decreased notably. These changes are beneficial as higher HDL levels and lower triglycerides can improve heart health.
These findings highlight the potential for vitamin D3 to play a positive role in managing cholesterol levels among IHD patients. While we noted these improvements in lipid profiles, the correlation between vitamin D levels and C-reactive protein, a marker of inflammation in the body, was not significant in our study, indicating that while vitamin D shows promise, more research is warranted.
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