Overview
SCIENTIFIC SCORE
Questionable
Based on 32 Researches
6.8
USERS' SCORE
Moderately Good
Based on 19 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
5
Total Fat
0.5 g
< 1%**
Vitamin A (from Retinyl Palmitate and Cod Liver Oil)
750 mcg
83%
Vitamin D3 (from Cholecalciferol and Cod Liver Oil)
6.75 mcg (270 IU)
34%
Cod Liver Oil
650 mg
†
Top Medical Research Studies
9
We explored the effects of all-trans retinoic acid (atRA) on atherosclerosis in rabbits fed a high-fat diet. In an experiment where rabbits were divided into groups, some received atRA while others received atorvastatin or both.
We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.
We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.
Read More
9
Vitamin A may help cholesterol levels
We examined the effects of a vitamin A-enriched diet on cholesterol levels in glucose-intolerant obese rats. Over a 14-week period, we fed two groups of rats—one received a standard diet, while the other enjoyed the vitamin A boost.
Our findings revealed that the vitamin A diet successfully lowered high cholesterol levels and improved HDL cholesterol, but it worked through different mechanisms than previously thought. Importantly, while we did see positive changes, the study indicates that the benefits may vary based on individual factors.
Our findings revealed that the vitamin A diet successfully lowered high cholesterol levels and improved HDL cholesterol, but it worked through different mechanisms than previously thought. Importantly, while we did see positive changes, the study indicates that the benefits may vary based on individual factors.
Read More
9
We investigated how vitamin D3 supplements impact cholesterol levels in pediatric patients suffering from obesity. The study involved 723 children over two years, with 283 receiving vitamin D3 and 440 on a placebo.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
Read More
Most Useful Reviews
10
Healthy skin
2 people found this helpful
This product is excellent and has greatly benefited me. My skin, hair, and nails are healthier, and my good cholesterol has increased. The quantity is large, meaning it lasts a long time, and the price is very affordable. I highly recommend it.
Read More
9
Eczema reduction
2 people found this helpful
I ordered this supplement for the first time and found its quality and quantity exceptional for the price. It significantly reduced my eczema inflammation and is beneficial for hair health due to its omega-3. I recommend taking it with food to avoid the oily aftertaste.
Read More
9
Cholesterol management
2 people found this helpful
A large jar of 250 capsules, excellent omega 3 quality. I take 2 capsules and feel better, as my cholesterol levels have decreased. For heart problems, a daily dose of at least 3 grams of omega 3 is necessary to lower "bad" cholesterol.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 32 Researches
6.8
- All Researches
9
Cod liver oil aids cholesterol reduction
We conducted an insightful study to examine the effects of cod liver oil on high cholesterol levels. The research was carried out in a well-structured manner, with 600 participants who had elevated cholesterol and low-density lipoprotein (LDL) levels. These individuals were divided into two groups. One group received daily doses of 415 mg of cod liver oil along with 10 mg of rosuvastatin, while the other group received just the rosuvastatin with placebo capsules.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
Read More
9
We explored the effects of all-trans retinoic acid (atRA) on atherosclerosis in rabbits fed a high-fat diet. In an experiment where rabbits were divided into groups, some received atRA while others received atorvastatin or both.
We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.
We found that atRA effectively reduced plaque size, comparable to atorvastatin, and their combination was even more effective. Additionally, atRA improved the serum lipid profile, suggesting it could be a valuable tool in managing cholesterol levels.
Read More
9
Vitamin A may help cholesterol levels
We examined the effects of a vitamin A-enriched diet on cholesterol levels in glucose-intolerant obese rats. Over a 14-week period, we fed two groups of rats—one received a standard diet, while the other enjoyed the vitamin A boost.
Our findings revealed that the vitamin A diet successfully lowered high cholesterol levels and improved HDL cholesterol, but it worked through different mechanisms than previously thought. Importantly, while we did see positive changes, the study indicates that the benefits may vary based on individual factors.
Our findings revealed that the vitamin A diet successfully lowered high cholesterol levels and improved HDL cholesterol, but it worked through different mechanisms than previously thought. Importantly, while we did see positive changes, the study indicates that the benefits may vary based on individual factors.
Read More
9
Vitamin D3 reduces triglycerides and cholesterol
We evaluated how vitamin D3 supplementation influences cholesterol levels in overweight or obese women through a comprehensive meta-analysis of randomized controlled trials. Our focus was on understanding whether this vitamin could effectively improve lipid profiles, specifically high cholesterol levels.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
In analyzing 13 studies, we found that vitamin D3 supplementation significantly reduced triglyceride (TG) and total cholesterol (TC) levels while also increasing high-density lipoprotein cholesterol (HDL-C), which is considered “good” cholesterol. Specifically, TG levels decreased by an average of about 6.13 mg/dL and total cholesterol levels decreased by approximately 4.45 mg/dL. Additionally, we saw a noteworthy boost in HDL-C levels, which increased by 1.54 mg/dL.
It's fascinating to note that the most notable reductions in triglycerides occurred in participants who started with higher baseline levels and those who were administered vitamin D3 for 26 weeks or less. However, we should be transparent that vitamin D3 did not show a significant effect on low-density lipoprotein cholesterol (LDL-C) concentrations, which is often a key concern in cholesterol management. Overall, our findings suggest that while vitamin D3 has a positive impact on certain aspects of lipid profiles, it may not be a comprehensive solution for all cholesterol issues.
Read More
9
We investigated how vitamin D3 supplements impact cholesterol levels in pediatric patients suffering from obesity. The study involved 723 children over two years, with 283 receiving vitamin D3 and 440 on a placebo.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
After closely examining the children’s cholesterol, triglycerides, and glucose levels, we found a strong relationship between these factors and their vitamin D3 levels. Following the supplementation, the group taking vitamin D3 experienced some notable improvements.
Specifically, we saw significant decreases in total cholesterol, HDL cholesterol, and triglycerides in the vitamin D3 group when compared to those who received the placebo. This indicates that vitamin D3 could play a beneficial role in managing high cholesterol and improving overall metabolic health in children coping with obesity.
Our findings suggest that vitamin D3 is a valuable addition to strategies aimed at improving lipid levels and encouraging healthy lifestyles in young patients struggling with excessive weight. Overall, supplementing with vitamin D3 appears to offer an effective approach to tackling high cholesterol in this at-risk population.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 19 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
10
Healthy skin
2 people found this helpful
This product is excellent and has greatly benefited me. My skin, hair, and nails are healthier, and my good cholesterol has increased. The quantity is large, meaning it lasts a long time, and the price is very affordable. I highly recommend it.
Read More
9
Eczema reduction
2 people found this helpful
I ordered this supplement for the first time and found its quality and quantity exceptional for the price. It significantly reduced my eczema inflammation and is beneficial for hair health due to its omega-3. I recommend taking it with food to avoid the oily aftertaste.
Read More
9
Cholesterol management
2 people found this helpful
A large jar of 250 capsules, excellent omega 3 quality. I take 2 capsules and feel better, as my cholesterol levels have decreased. For heart problems, a daily dose of at least 3 grams of omega 3 is necessary to lower "bad" cholesterol.
Read More
9
Cholesterol decrease
1 people found this helpful
My favourite omega 3 with good quality. I take 6 capsules and feel better. Since I have elevated cholesterol levels, a daily intake of 3 grams of omega 3 is essential to lower "bad" cholesterol.
Read More
7.5
Cholesterol decrease
3 people found this helpful
My cholesterol level was elevated, so I worked with my doctor to adjust my diet, exercise, and take dietary supplements. I included unrefined vegetable oils, omega-3, probiotics, and cod liver oil. After a month, my cholesterol began to decrease. I liked the product, and the price was reasonable.
Read More
Frequently Asked Questions
7.5
Cholesterol decrease
3 people found this helpful
My cholesterol level was elevated, so I worked with my doctor to adjust my diet, exercise, and take dietary supplements. I included unrefined vegetable oils, omega-3, probiotics, and cod liver oil. After a month, my cholesterol began to decrease. I liked the product, and the price was reasonable.
9
Cholesterol management
2 people found this helpful
A large jar of 250 capsules, excellent omega 3 quality. I take 2 capsules and feel better, as my cholesterol levels have decreased. For heart problems, a daily dose of at least 3 grams of omega 3 is necessary to lower "bad" cholesterol.
7.5
Heart health improvement
This omega improves blood vessel and heart health, significantly lowering cholesterol. The ingredients and quality are very good.
9
Eczema reduction
2 people found this helpful
I ordered this supplement for the first time and found its quality and quantity exceptional for the price. It significantly reduced my eczema inflammation and is beneficial for hair health due to its omega-3. I recommend taking it with food to avoid the oily aftertaste.
10
Healthy skin
2 people found this helpful
This product is excellent and has greatly benefited me. My skin, hair, and nails are healthier, and my good cholesterol has increased. The quantity is large, meaning it lasts a long time, and the price is very affordable. I highly recommend it.
7.5
Joint pain relief
2 people found this helpful
I recommend fish oil for my sister's joint issues, which she notices improving with regular use. It's effective for reducing inflammation and supporting heart health while also decreasing harmful cholesterol. The quality is excellent, and the packaging lasts a long time.
7.5
Good cod liver oil
Cod liver oil is very beneficial for high cholesterol. While it's of decent quality, I find it not to be the best.
9
Cod liver oil aids cholesterol reduction
We conducted an insightful study to examine the effects of cod liver oil on high cholesterol levels. The research was carried out in a well-structured manner, with 600 participants who had elevated cholesterol and low-density lipoprotein (LDL) levels. These individuals were divided into two groups. One group received daily doses of 415 mg of cod liver oil along with 10 mg of rosuvastatin, while the other group received just the rosuvastatin with placebo capsules.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
After 30 days, we observed compelling results. The group taking cod liver oil showed a more significant drop in total cholesterol levels compared to those who only took rosuvastatin. Specifically, their total cholesterol fell to 152.22 mg/dL compared to 171.65 mg/dL in the control group. Similarly, LDL levels decreased more in the cod liver oil group, highlighting its potential benefits when added to standard cholesterol treatment.
However, it's crucial to mention that while cod liver oil seems to enhance the effect of rosuvastatin, lifestyle changes should still be the primary focus for anyone managing high cholesterol. This study opens the door for further research to explore the specific benefits of cod liver oil in such treatments.
2
Cod liver oil ineffective for cholesterol
We examined how long-term supplementation with cod liver oil (CLO) affects cholesterol levels in individuals with moderate high cholesterol. Over 14 months, 120 participants consumed either CLO or seal oil daily, while a control group received no supplements.
While both oils improved serum fatty acid composition and reduced platelet aggregation compared to the control, neither CLO nor seal oil led to significant changes in total cholesterol or other lipids. Overall, cod liver oil alone does not appear to effectively lower cholesterol levels in hypercholesterolemic individuals.
While both oils improved serum fatty acid composition and reduced platelet aggregation compared to the control, neither CLO nor seal oil led to significant changes in total cholesterol or other lipids. Overall, cod liver oil alone does not appear to effectively lower cholesterol levels in hypercholesterolemic individuals.
4
We conducted a study to investigate how cod liver oil, among other marine oils, affects cholesterol levels. In this research, healthy participants consumed various oils, including cod liver oil and seal oil, for ten weeks. While total cholesterol levels remained unchanged across all the oil groups, we observed notable increases in high-density lipoprotein (HDL) cholesterol, particularly in the seal/cod liver oil group, which saw a 7% increase, and an 11% increase in the whale oil group.
Interestingly, while cod liver oil didn’t significantly impact total cholesterol, it was part of a combination that led to reduced triacylglycerol levels. We also noted that whale oil supplementation reduced prothrombin fragment 1 + 2 levels by 25%, indicating a potential benefit in coagulation.
However, cod liver oil alone did not have a significant impact on reducing certain inflammatory responses and thromboxane B2 levels, which are associated with cardiovascular health. Thus, while cod liver oil shows potential benefits when combined with other oils, further studies are needed to clarify its specific effects on cholesterol levels on its own.
Interestingly, while cod liver oil didn’t significantly impact total cholesterol, it was part of a combination that led to reduced triacylglycerol levels. We also noted that whale oil supplementation reduced prothrombin fragment 1 + 2 levels by 25%, indicating a potential benefit in coagulation.
However, cod liver oil alone did not have a significant impact on reducing certain inflammatory responses and thromboxane B2 levels, which are associated with cardiovascular health. Thus, while cod liver oil shows potential benefits when combined with other oils, further studies are needed to clarify its specific effects on cholesterol levels on its own.
8
We conducted a study to explore how cod liver oil might impact cholesterol levels during pregnancy and lactation. In this study, we recruited 590 pregnant women, some of whom received daily supplements of cod liver oil rich in omega-3 fatty acids, while others were given corn oil, which is high in omega-6 fatty acids.
Our findings revealed that the women taking cod liver oil showed a significant increase in the levels of docosahexaenoic acid (DHA) in both their own blood and in the blood of their infants. Interestingly, the women who supplemented with cod liver oil experienced a less pronounced increase in plasma triacylglycerol, a type of fat in the blood, compared to those taking corn oil.
Furthermore, while the level of high-density lipoprotein (HDL) cholesterol remained stable in the cod liver oil group, it decreased in the corn oil group. This change in cholesterol levels is important because HDL is often referred to as "good" cholesterol, and maintaining its levels can support heart health.
Overall, we observed that supplementing with cod liver oil not only boosts DHA levels for the baby but also helps keep maternal cholesterol levels more favorable during pregnancy. This suggests that cod liver oil may be a beneficial option for pregnant women looking to support their health and that of their infants.
Our findings revealed that the women taking cod liver oil showed a significant increase in the levels of docosahexaenoic acid (DHA) in both their own blood and in the blood of their infants. Interestingly, the women who supplemented with cod liver oil experienced a less pronounced increase in plasma triacylglycerol, a type of fat in the blood, compared to those taking corn oil.
Furthermore, while the level of high-density lipoprotein (HDL) cholesterol remained stable in the cod liver oil group, it decreased in the corn oil group. This change in cholesterol levels is important because HDL is often referred to as "good" cholesterol, and maintaining its levels can support heart health.
Overall, we observed that supplementing with cod liver oil not only boosts DHA levels for the baby but also helps keep maternal cholesterol levels more favorable during pregnancy. This suggests that cod liver oil may be a beneficial option for pregnant women looking to support their health and that of their infants.
7
We explored the impact of dietary cod liver oil on cholesterol levels and other health factors in patients with insulin-dependent diabetes and albuminuria. In a carefully controlled double-blind crossover study, participants received either cod liver oil or olive oil over eight weeks. This setup ensured that we could accurately assess the effects of the supplements without bias.
During the study, we observed that cod liver oil significantly increased levels of high-density lipoprotein (HDL) cholesterol, often referred to as "good" cholesterol. Additionally, there were decreases in very-low-density lipoprotein (VLDL) cholesterol and triglycerides, which are often associated with heart health. On the other hand, the olive oil group did not show similar improvements; instead, they experienced a decrease in low-density lipoprotein (LDL) cholesterol, or "bad" cholesterol, alongside increases in VLDL and triglycerides.
However, it's important to note that while cod liver oil showed some promise in improving certain cholesterol measures, it did not have a noticeable effect on overall urinary albumin excretion, which is a key marker in diabetes management. This suggests that while cod liver oil may be beneficial for cholesterol levels, its overall impact on diabetic-related conditions remains limited.
Overall, dietary supplementation with cod liver oil can provide some cholesterol-related benefits, but we did not find significant changes in key diabetes markers throughout the study.
During the study, we observed that cod liver oil significantly increased levels of high-density lipoprotein (HDL) cholesterol, often referred to as "good" cholesterol. Additionally, there were decreases in very-low-density lipoprotein (VLDL) cholesterol and triglycerides, which are often associated with heart health. On the other hand, the olive oil group did not show similar improvements; instead, they experienced a decrease in low-density lipoprotein (LDL) cholesterol, or "bad" cholesterol, alongside increases in VLDL and triglycerides.
However, it's important to note that while cod liver oil showed some promise in improving certain cholesterol measures, it did not have a noticeable effect on overall urinary albumin excretion, which is a key marker in diabetes management. This suggests that while cod liver oil may be beneficial for cholesterol levels, its overall impact on diabetic-related conditions remains limited.
Overall, dietary supplementation with cod liver oil can provide some cholesterol-related benefits, but we did not find significant changes in key diabetes markers throughout the study.
References
- Fatima F, Memon A, Zafar S, Amar Z, Talpur AS, et al. Role of Cod Liver Oil in Reducing Elevated Lipid Parameters. Cureus. 2021;13:e15556. 10.7759/cureus.15556
- Kontostathi M, Isou S, Mostratos D, Vasdekis V, Demertzis N, et al. Influence of Omega-3 Fatty Acid-Rich Fish Oils on Hyperlipidemia: Effect of Eel, Sardine, Trout, and Cod Oils on Hyperlipidemic Mice. J Med Food. 2021;24:749. 10.1089/jmf.2020.0114
- Helland IB, Saugstad OD, Saarem K, Van Houwelingen AC, Nylander G, et al. Supplementation of n-3 fatty acids during pregnancy and lactation reduces maternal plasma lipid levels and provides DHA to the infants. J Matern Fetal Neonatal Med. 2006;19:397.
- Thorsdottir I, Gunnarsdottir I, Palsson GI. Birth weight, growth and feeding in infancy: relation to serum lipid concentration in 12-month-old infants. Eur J Clin Nutr. 2003;57:1479.
- Brox J, Olaussen K, Osterud B, Elvevoll EO, Bjørnstad E, et al. A long-term seal- and cod-liver-oil supplementation in hypercholesterolemic subjects. Lipids. 2001;36:7.
- Vognild E, Elvevoll EO, Brox J, Olsen RL, Barstad H, et al. Effects of dietary marine oils and olive oil on fatty acid composition, platelet membrane fluidity, platelet responses, and serum lipids in healthy humans. Lipids. 1998;33:427.
- Chicco A, D'Alessandro ME, Karabatas L, Gutman R, Lombardo YB. Effect of moderate levels of dietary fish oil on insulin secretion and sensitivity, and pancreas insulin content in normal rats. Ann Nutr Metab. 1996;40:61.
- Osterud B, Elvevoll E, Barstad H, Brox J, Halvorsen H, et al. Effect of marine oils supplementation on coagulation and cellular activation in whole blood. Lipids. 1995;30:1111.
- Kim DN, Schmee J, Baker JE, Lunden GM, Sheehan CE, et al. Dietary fish oil reduces microthrombi over atherosclerotic lesions in hyperlipidemic swine even in the absence of plasma cholesterol reduction. Exp Mol Pathol. 1993;59:122.
- Hansen JB, Berge LN, Svensson B, Lyngmo V, Nordøy A. Effects of cod liver oil on lipids and platelets in males and females. Eur J Clin Nutr. 1993;47:123.
- Kim DN, Schmee J, Lee CS, Eastman A, Ross JS, et al. Comparison of effects of fish oil and corn oil supplements on hyperlipidemic diet induced atherogenesis in swine. Atherosclerosis. 1991;89:191.
- Hansen JB, Svensson B, Wilsgård L, Osterud B. Serum enriched with n-3 polyunsaturated fatty acids inhibits procoagulant activity in endothelial cells. Blood Coagul Fibrinolysis. 1991;2:515.
- Jensen T, Stender S, Goldstein K, Hølmer G, Deckert T. Partial normalization by dietary cod-liver oil of increased microvascular albumin leakage in patients with insulin-dependent diabetes and albuminuria. N Engl J Med. 1989;321:1572.
- Komori K, Shimokawa H, Vanhoutte PM. Endothelium-dependent relaxation in response to aggregating platelets in porcine femoral veins and its modulation by diet. Circulation. 1989;80:401.
- Shimokawa H, Vanhoutte PM. Dietary cod-liver oil improves endothelium-dependent responses in hypercholesterolemic and atherosclerotic porcine coronary arteries. Circulation. 1988;78:1421.
- Simonsen T, Nordøy A, Sjunneskog C, Lyngmo V. The effect of cod liver oil in two populations with low and high intake of dietary fish. Acta Med Scand. 1988;223:491.
- Sarkisova EA, Chumak AA, Ovsyannikova LM, Alekhina LM, Nosach OV, et al. THE EFFECT OF APPLICATION OF ANTIOXIDANT THERAPY IN THE TREATMENT OF NON-ALKOHOLIC STEATOHEPATATIS IN CHORNOBYL NPP ACCIDENT SUFFERERS IN THE REMOTE PERIOD AFTER IRRADIATION. Probl Radiac Med Radiobiol. 2018;23:452. 10.33145/2304-8336-2018-23-452-461
- Zarei L, Bahrami M, Farhad N, Froushani SMA, Abbasi A. All-trans retinoic acid effectively reduces atheroma plaque size in a rabbit model of high-fat-induced atherosclerosis. Adv Clin Exp Med. 2018;27:1631. 10.17219/acem/74552
- Jeyakumar SM, Sheril A, Vajreswari A. Chronic vitamin A-enriched diet feeding regulates hypercholesterolaemia through transcriptional regulation of reverse cholesterol transport pathway genes in obese rat model of WNIN/GR-Ob strain. Indian J Med Res. 2016;144:238. 10.4103/0971-5916.195038
- Prashanth A, Jeyakumar SM, Giridharan NV, Vajreswari A. Vitamin A-enriched diet modulates reverse cholesterol transport in hypercholesterolemic obese rats of the WNIN/Ob strain. J Atheroscler Thromb. 2014;21:1197.
- Syed NI, Arshad S, Syed AA, Ahmad M, Khan FZ, et al. A comparative study of antioxidant vitamins and simvastatin in hypercholesterolimic rabbits. Pak J Pharm Sci. 2011;24:479.
- Hu L, Velu P, Prabahar K, Hernández-Wolters B, Kord-Varkaneh H, et al. Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials. Nutr Rev. 2025. 10.1093/nutrit/nuae226
- Wang F, Bei L, Zhang X, Fu Y. Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity. Crit Rev Immunol. 2025;45:31. 10.1615/CritRevImmunol.2024052129
- Sadeghi M, Momeni A, Mirsaeidi FS, Jamalian M, Amirpour A, et al. The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial. Adv Biomed Res. 2024;13:79. 10.4103/abr.abr_380_23
- Xu W, Wang L, Yang L, Li X, Li C, et al. [Vitamin D3 alleviates the gastritis that associated with Helicobacter pylori infection in mice with hypercholesterolemia by enhancing the activity of vitamin D receptors in the liver tissue and blocking the signaling pathway of JAK/STAT3]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2024;40:520.
- Papakonstantinou E, Zacharodimos N, Georgiopoulos G, Athanasaki C, Bothou DL, et al. Two-Month Consumption of Orange Juice Enriched with Vitamin D3 and Probiotics Decreases Body Weight, Insulin Resistance, Blood Lipids, and Arterial Blood Pressure in High-Cardiometabolic-Risk Patients on a Westernized Type Diet: Results from a Randomized Clinical Trial. Nutrients. 2024;16. 10.3390/nu16091331
- Oczkowicz M, Szymczyk B, Świątkiewicz M, Wierzbicka A, Steg A, et al. Effect of vitamin D3 supplementation on blood parameters and liver gene expression in female rats. Mol Biol Rep. 2024;51:456. 10.1007/s11033-024-09408-6
- Yang HE, Lee BW, Choi IJ, Oh JY, An EJ. Age-dependent effect of vitamin D supplementation on musculoskeletal health in chronic spinal cord injury patients: A pilot study. J Spinal Cord Med. 2025;48:93. 10.1080/10790268.2023.2257850
- Habiba E, Ali S, Ghanem Y, Sharaki O, Hewedy W. Effect of oral versus parenteral vitamin D3 supplementation on nuclear factor-κB and platelet aggregation in type 2 diabetic patients. Can J Physiol Pharmacol. 2023;101:610. 10.1139/cjpp-2022-0359
- Sandgruber F, Höger AL, Kunze J, Schenz B, Griehl C, et al. Impact of Regular Intake of Microalgae on Nutrient Supply and Cardiovascular Risk Factors: Results from the NovAL Intervention Study. Nutrients. 2023;15. 10.3390/nu15071645
- Zhou Z, Nagashima T, Toda C, Kobayashi M, Suzuki T, et al. Vitamin D supplementation is effective for olanzapine-induced dyslipidemia. Front Pharmacol. 2023;14:1135516. 10.3389/fphar.2023.1135516
- Hariri Z, Kord-Varkaneh H, Alyahya N, Prabahar K, Găman MA, et al. Higher Dietary Vitamin D Intake Influences the Lipid Profile and hs-CRP Concentrations: Cross-Sectional Assessment Based on The National Health and Nutrition Examination Survey. Life (Basel). 2023;13. 10.3390/life13020581
